The purpose of this study is to predict the amount of primary air pollution substances in Seoul, Korea. An artificial neural network (ANN) was used as a prediction method. The ANN with three layers is teamed with past data, and the concentrations of air pollutants are predicted based on the pre-teamed weights. The error back propagation method that has a powerful application to various fields was adopted as the loaming rule. The concentrations of air pollutants from one to six hours in the future were predictcd with the ANN. To verify the performance of the prediction method used in the present study, the predicted concentrations of air pollutants were compared with the measured data. From the comparison, it was found that the prediction method based on the ANN gives an acceptable accuracy for the limited prediction horizon.