Two methods of inverse supercritical fluid chromatography (ISFC), frontal analysis supercritical fluid chromatography (SFC) and elution SFC, have been compared for the determination of distribution coefficients of solutes between a polymer and a supercritical CO2. The logarithm of the distribution coefficient showed monotonic decrease with the density of the supercritical fluid (SF). The abnormal-maximum behavior of solute sorption in the polymer phase was explained by the fluid and solute properties, f2P/P2 sat. Interesting open-elliptic shapes of sorption and volumefraction curves were obtained and explained with the fugacity coefficient. Correction to the capacity factor was employed to eliminate the retention due to the adsorption on the surface of the silica support. A model based on the Flory equation and the Peng-Robinson equation of state (EOS) successfully predicted the phase behavior of the ternary solutesupercritical fluid-polymer systems using only interaction parameters obtained from the binary systems. The solute
distribution coefficient at infinite dilution was used to calculate the phase equilibrium at finite concentration using a ternary-phase diagram.
Bartle KD, "Theory and Principles of Supercritical Fluid Chromatography," in Supercritical Fluid Chromatography-(RSC Chromatography Monographs), Smith, R.M., Ed., The Royal Society of Chemistry, London, chap. 1, 1988
Berens AR, Huvard GS, "Interaction of Polymers with Near-Critical Carbon Dioxide," in Supercritical Fluid Science and Technology,Johnston, K.P. and Penninger, J.M.L., eds., ACS Symposium Series 406, American Chemical Society, Washington, D.C., 207, 1989
Berens AR, Huvard GS, Korsmeyer RW, "Application of Compressed Carbon Dioxide in the Incorporation of Additive into Polymers," Paper No. 48b, AIChE Meet., Washington, DC, 1988
Shim JJ, "Thermodynamics and Phase Equilibria of Polymer-Solute-Supercritical Fluid Systems by Supercritical Fluid Chromatography," Ph.D. Dissertation, University of Texas at Austin, Austin, Texas, 1990
Shim JJ, Johnston KP, AIChE J., 35(7), 1097, 1989
Shim JJ, Johnston KP, J. Phys. Chem., 95(1), 353, 1991