Aminated cassava residue magnetic microspheres (ACRPM) were synthesized via an inverse emulsion method by using chemically modified cassava residue as a crude material, and acrylic acid (AA), acrylamide (AM), and methyl methacrylate (MMA) as monomers and a polyethylene glycol/methanol system (PEG/MeOH) as the porogen. Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), N2 adsorption-desorption and vibrating sample magnetometry (VSM) were used to characterize the ACRPM. The results indicated that amino groups were grafted to the cassava residue magnetic microspheres, and the Fe3O4 nanoparticles were encapsulated in the microspheres. After porogen was added, the particle size of the ACRPM decreased from 16.5 꺷m to 150 nm with a pore volume of 0.05510m3/g, and the specific surface area of the ACRPM increased from 3.02 to 12.34m2/g. The ACRPM were superparamagnetic, and the saturation magnetization was 9.8 emu/g. The maximum adsorption capacity of Pb(II) on the ACRPM was 390mg/g. The ACRPM exhibited a large specific surface area and provided many adsorption sites for metal ion adsorption, which favored a high adsorption capacity. Additionally, the Pb(II) adsorption process was fitted to pseudo-second-order kinetic and Langmuir isothermal adsorption models. This suggests that the Pb(II) adsorption process was dominated by a chemical reaction process and that chemisorption was the rate-controlling step during the Pb(II) removal process. In addition, the adsorbent exhibited good stability after six consecutive reuses.