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Issue
Korean Journal of Chemical Engineering,
Vol.33, No.10, 2908-2914, 2016
Potential industrial application of Actinobacillus succinogenes NJ113 for pyruvic acid production by microaerobic fermentation
Wang Z, Xiao W, Zhang A, Ying H, Chen K, Ouyang P
Actinobacillus succinogenes NJ113 is capable of microaerobic fermentation, which offers the possibility of a novel type of pyruvic acid production. A dissolved oxygen environment with stirring at 300 rpm was a key factor in the fermentative production of a maximum concentration of pyruvic acid. Potassium carbonate (K2CO3) was found to have a role in promoting pyruvic acid production, influencing the concentration of pyruvic acid and production of the by-product succinic acid. The final titer of pyruvic acid production was 36.8±0.1 g L-1 with an overall yield of 0.639±0.056 g g-1 glucose and 3.12±0.03mmol g-1 dry cell weight h-1. Significance and impact of the study: This study is the first to illustrate the advantage of using Actinobacillus succinogenes NJ113 with no genetic modification under microaerobic conditions for the production of pyruvic acid.
Keywords: Actinobacillus succinogenes; Dissolved Oxygen Environment; Microaerobic Fermentation; Potassium Carbonate; Pyruvic Acid
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