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Issue
Korean Journal of Chemical Engineering,
Vol.33, No.8, 2253-2267, 2016
Recent advances for serial processes of hazardous chemicals in fully integrated microfluidic systems
Singh R, Lee HJ, Singh AK, Kim DP
The development and enlargement of toxic and hazardous chemicals are severely limited by health and safety concerns. We summarize studies on fully integrated micro-chemical systems and total processes to reduce accidental exposure to various regents that are toxic, explosive, or carcinogenic, which significantly improved the safety of work involving risky compounds. This review covers the leak-free continuous-flow processes of hazardous chemicals in fully integrated microfluidic systems, specially denoted as micro-total envelope systems (μ-TESs), that are conducting a serial process of the generation of hazardous reagents, in-situ purification and separation, subsequent reaction, and product isolation with improved efficiencies. These attempts suggest safe and efficient tools and processes of useful but hazardous chemicals for researchers and manufacturing workers in the field of pharmaceutic discovery, natural products, biology as well as materials synthesis.
Keywords: Toxic Chemicals; Total Process System; Micro-total Envelopment System; Separator; Extraction Unit; Tube in Tube System; Dual Channel Microreactor; Silicon Nanowire Reactor; Diaze Compound; Azide; Carbon Monoxide; Ozone; Chloro Methyl Methyl Ether
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[Cited By]
  1. Park K, Korean Journal of Chemical Engineering, 34(3), 642, 2017
  2. Lee BJ, Jin SH, Jeong SG, Kang KK, Lee CS, Korean Chemical Engineering Research, 55(6), 791, 2017
  3. Jeong SG, Jeong JH, Kang KK, Jin SH, Lee BJ, Choi CH, Lee CS, Korean Journal of Chemical Engineering, 35(10), 2036, 2018
  4. Behdani B, Monjezi S, Zhang J, Wang C, Park JT, Korean Journal of Chemical Engineering, 37(12), 2117, 2020
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