To investigate the performance of a jet loop reactor with the two-fluid swirl nozzle (TSN), CO2 absorption experiments in an alkaline solution were performed. The experimental results obtained in the reactor were compared with those in a jet loop reactor with the two-fluid conventional nozzle (TCN). The neutralization time of alkaline solution and the CO2 removal efficiency were used as the indices for a comparison of the reactor performance. Due to the swirling flow, the neutralization times of alkaline solutions by CO2 in the reactor with the TSN were shortened compared with those in the reactor with the TCN. Also, the instantaneous and/or overall CO2 removal efficiencies in the reactor with the TSN were higher than those in the reactor with the TCN at the same liquid circulation flow rate.