Korean Journal of Chemical Engineering, Vol.30, No.10, 1836-1842, 2013
Optimization of temperature swing strategy for selective cooling crystallization of α-form L-glutamic acid crystals
L-glutamic acid can be crystallized as metastable α-form and stable β-form crystal. The α-form is desired because of its prismatic shape. Production of α-form of L-glutamic acid by cooling crystallization is not well-defined and α-form solid is commercially not available. In this study, an optimal cooling strategy to selectively produce large and narrowly distributed α-crystals is found by modeling and optimizing the crystallization and polymorphic transformation of L-glutamic acid. The optimal temperature profile is found to be cooling-heating-cooling concept where short nucleation period is followed by growth period in metastable zone. The obtained α-form of L-glutamic acid by optimal strategy had improved mean size, distribution, and purity compared to constant cooling.
[References]
Dharmayat D, Hammond RB, Lai X, Ma C, Purba E, Roberts KJ, Chen ZP, Martin E, Morris J, Bytheway R, Cryst. Growth Des. , 8 (7), 2205, 2008
Srinivasan K, J. Cryst. Growth , 311 (1), 156, 2008
O’Mahony MA, Maher A, Croker DM, Rasmuson AC, Hodnett BK, Cryst. Growth Des. , 12 (4), 1925, 2012
Sypek K, Burns IS, Florence AJ, Sefcik J, Cryst. Growth Des. , 12 (10), 4821, 2012
De Anda JC, Wang XZ, Lai X, Roberts KJ, J. Process Control , 15 (7), 785, 2005
Garti N, Zour H, J. Cryst. Growth. , 172 , 486, 1997
Kitamura M, J. Cryst. Growth. , 96 , 541, 1989
Cashell C, Corcoran D, Hodnett BK, Chem. Commun. , 3 , 374, 2003
Roelands CPM, ter Horst JH, Kramer HJM, Jansens PJ, AIChE J. , 53 (2), 354, 2007
Cornel J, Lindenberg C, Mazzotti M, Cryst. Growth Des. , 9 (1), 243, 2009
Hatakka H, Alatalo H, Louhi-Kultanen M, Lassila I, Haeggstrom E, Chem. Eng. Technol. , 33 (5), 751, 2010
Mo YX, Dang LP, Wei HY, Fluid Phase Equilib. , 300 (1-2), 105, 2011
De Anda JC, Wang XZ, Lai X, Roberts KJ, Jennings KH, Wilkinson MJ, Watson D, Roberts D, AIChE J. , 51 (5), 1406, 2005
Kee NCS, Tan RBH, Braatz RD, Cryst. Growth Des. , 9 (7), 3044, 2009
Yang DR, Lee KS, Lee JS, Kim SG, Kim DH, Bang YK, Ind. Eng. Chem. Res. , 46 (24), 8158, 2007
Kim DY, Paul M, Repke JU, Wozny G, Yang DR, Korean J. Chem. Eng. , 26 (5), 1220, 2009
Worlitschek J, Mazzotti M, Cryst. Growth Des. , 4 (5), 891, 2004
Czapla F, Haida H, Elsner MP, Lorenz H, Seidel-Morgenstern A, Chem. Eng. Sci. , 64 (4), 753, 2009
Liu JJ, Ma CY, Hu YD, Wang XZ, Chem. Eng. Res. Des. , 88 (4A), 437, 2010
Ma CY, Wang XZ, Roberts KJ, Adv. Powder Technol. , 18 (6), 707, 2007
Ma CY, Wang XZ, Chem. Eng. Sci. , 70 , 22, 2012
Kumar S, Ramkrishna D, Chem. Eng. Sci. , 51 (8), 1333, 1996
Kumar S, Ramkrishna D, Chem. Eng. Sci. , 52 (24), 4659, 1997
Gerstlauer A, Mitrovic A, Motz S, Gilles ED, Chem. Eng. Sci. , 56 (7), 2553, 2001
McCoy BJ, J. Colloid Interface Sci. , 240 (1), 139, 2001
McCoy BJ, Chem. Eng. Sci. , 57 (12), 2279, 2002
Madras G, McCoy BJ, Powder Technol. , 143-144 , 297, 2004
Puel F, Fevotte G, Klein JP, Chem. Eng. Sci. , 58 (16), 3715, 2003
Puel F, Fevotte G, Klein JP, Chem. Eng. Sci. , 58 (16), 3729, 2003
Gunawan R, Fusman I, Braatz RD, AIChE J. , 50 (11), 2738, 2004
Hu Q, Rohani S, Wang DX, Jutan A, AIChE J. , 50 (8), 1786, 2004
Hu Q, Rohani S, Jutan A, AIChE J. , 51 (11), 3000, 2005
Fevotte F, Fevotte G, Chem. Eng. Sci. , 65 (10), 3191, 2010
Silva LFLR, Rodrigues RC, Mitre JF, Lage PLC, Comput. Chem. Eng. , 34 (3), 286, 2010
Samad NAFA, Singh R, Sin G, Gernaey KV, Gani R, Comput. Chem. Eng. , 35 (5), 828, 2011
Scholl J, Bonalumi D, Vicum L, Mazzotti M, Muller M, Cryst.Growth Des. , 6 (4), 881, 2006
Hermanto MW, Kee NC, Tan RBH, Chiu MS, Braatz RD, AIChE J. , 54 (12), 3248, 2008
Qamar S, Noor S, Seidel-Morgenstern A, Ind. Eng. Chem. Res. , 49 (10), 4940, 2010
Nagy ZK, Aamir E, Rielly CD, Cryst. Growth Des. , 11 , 2205, 2011
이전 논문 다음 논문
Result Search