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Issue
Korean Journal of Chemical Engineering,
Vol.30, No.2, 422-428, 2013
Preparation of nylon-6/chitosan composites by nanospider technology and their use as candidate for antibacterial agents
Al-Deyab SS, El-Newehy MH, Nirmala R, Abdel-Megeed A, Kim HY
Electrospun nylon-6/chitosan (nylon-6/Ch) nanofibers were prepared by nanospider technology. Quaternary ammonium salts as antibacterial agent were immobilized onto electrospun nylon-6/Ch nanofibers via surface modification by soaking the mat in aqueous solution of glycidyltrimethylammonium chloride (GTMAC) at room temperature overnight to give nylon-6/N-[(2-hydroxy-3-trimethylammonium)propyl] chitosan chloride (nylon-6/HTCC). The morphological, structural and thermal properties of the nylon-6/ch nanofibers were studied by field-emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), Fourier transform-infrared (FT-IR) spectroscopy, and thermogravimetric analysis (TGA). Biological screening has demonstrated the antibacterial activity of the electrospun nanofibers against Gram negative bacteria, Escherichia coli 35218, and Pseudomonas aeruginosa and Gram positive bacteria, Staphylococcus aureus 24213 among the tested microbes. Thus, the study ascertains the value of the use of electrospun nanofibers, which could be of considerable interest to the development of new antibacterial materials for biomedical applications.
Keywords: Chitosan; Nylon-6; Onium Salts; Antibacterial Polymers
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[Cited By]
  1. Lee KR, Song KH, Korean Journal of Chemical Engineering, 31(1), 162, 2014
  2. Jeong GT, Korean Chemical Engineering Research, 52(3), 355, 2014
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