Print: | ISSN 0256-1115 |
Online: | ISSN 1975-7220 |
Korean Journal of Chemical Engineering,
Vol.25, No.5, 980-981, 2008 Thermal decomposition kinetics of 5-fluorouracil from thermogravimetric analysis
The thermal decomposition kinetics of 5-fluorouracil was studied by thermogravimetric analysis methodology. The decomposition activation energy was calculated by using Ozawa method by means of TGA in nitrogen atmosphere. Moreover, the decomposition mechanism and pre-factor were obtained by Coats-Redfern and Achar methods, respectively. It is found that the decomposition activation energy of fluorouracil is 105 kJ·mol.1. The decomposition mechanisms obtained by Coats-Redfern and Achar methods are G(α)=[-ln(1-α)]2/3 and f(α)=1.5(1-α)[-ln(1-α)1/3 respectively, lnA is 21.40 min-1.
Keywords:
5-Fluorouracil; Thermal Degradation Kinetics; Decomposition Activation Energy; Solid-state Function
[References]
|