The hydrodeoxygenation (HDO) reaction plays a crucial role in the catalytic upgrading of bio-derived platform chemicals

to renewable fuels and chemicals. Given its industrial versatility, the production of primary alcohols via the catalytic 

hydrodeoxygenation of carboxylic acids has been explored using the RuSn/ZnO catalyst demonstrating high performance 

and robust stability in high-pressure continuous-fl ow reaction systems. However, the complex synthesis procedures of this 

catalyst impose limitations on its applicability and scalability. Additionally, powder catalysts could cause a pressure drop 

across the catalytic beds, causing another challenge in a large-scale operation. To address these issues, a simplifi ed preparation

method for RuSn/ZnO catalyst utilizing commercial support was developed and pelletized sing methylcellulose and 

bentonite as binder. The pellet catalysts, with varying binder ratios (wt binder /wt cat ), were evaluated for the hydrodeoxygenation 

of hexanoic acid under diff erent reaction conditions. Characterization results confi rmed the formation of Ru 3 Sn 7 alloy on 

the RuSn/ZnO-5 (wt binder /wt cat = 0.05) catalyst, which selectively produced 1-hexanol with a yield of 72.7% under optimized 

reaction conditions. Notably, the RuSn/ZnO-30 catalyst could selectively produce biofuel components (1-hexanol and hexyl 

hexanoate) with high stability in 0.403 L/day of hexanoic acid hydrodeoxygenation. The developed catalytic system off ers the 

potential for advancing biomass conversion as a viable alternative to the conventional petrochemical processes, contributing 

to the industrialization of sustainable fuels and chemicals production.