Gas hydrates, crystalline inclusion compounds formed under specific thermodynamic conditions, have garnered growing

interest as a sustainable and energy-efficient medium for gas separation processes. This review presents a comprehensive

examination of hydrate-based separation technologies, with a focus on hydrogen (

H2) separation from methane (

CH4) and

carbon dioxide (

CO2) mixtures. The fundamental structures and properties of clathrate hydrates are first introduced, followed

by a discussion of pure hydrates and their limitations for practical gas separation. The review then addresses the

role of binary hydrates, where guest molecule combinations enhance hydrate formation and selectivity, and semi-clathrate

hydrates, where ionic promoters like tetra-n-butylammonium bromide (TBAB) lower the formation pressure and influence

gas selectivity. Special attention is paid to the thermodynamic and kinetic behaviors of H2

+ CH4

and H2

+ CO2

systems in

various hydrate environments. The synergistic effects of additional components such as cyclopentane (CP) and surfactants

like sodium dodecyl sulfate (SDS) are analyzed for their ability to enhance gas uptake and separation efficiency. Finally, the

review covers advances in hydrate formation within porous supports such as silica gels, which offer a promising pathway

to overcome kinetic barriers and facilitate static, low-energy operation. Overall, this article consolidates key findings and

experimental insights to provide a current understanding of the hydrate-based hydrogen separation field, offering a valuable

resource for further development and application.