An alternate method for preparative chromatography, moving feed-injection system was studied with a modified plate model and was compared with the conventional preparative case. Experiments were performed for the separation of diethylether and dichloromethane by a gas-liquid chromatography. The moving feed technique had some advantages over the conventional preparative system; decreased bandwidths, higher peak maxima, and better resolution.
The moving feed chromatography can be optimized by variation of the feed port velocities. A plate model was used successfully to predict the experimental concentration profiles. The effects of the particle size were also studied experimentally.