Titanium silicalite 1 catalysts were prepared using various hydrothermal synthesis methods and the effects of synthesis parameters on the catalyst morphology were investigated. XRD, SEM, IR, 29Si MAS NMR, UV-VIS DRS, and EXAFS analysis were then performed to evaluate its physico-chemical properties. For its catalytic property study, liquid phase n-hexane oxidation using H2O2 as oxidant was carried out. It was established that an adequate amount of TPAOH, alkoxide silicon source, continuous water replenishment during the hydrolysis process and fast heating of the hydrothemal reactor vessel are necessary in order to obtain small zeolite crystals. In the n-hexane oxidation, 2,3-hexanol and 2,3-hexanone were produced via successive oxidation sequences, and 2-hexanol was found to be more quickly oxidized to ketone than 3-hexanol. Methanol and acetone were superior as a solvent, and under non-excess solvent condition, n-hexane/H₂O₂ mole ratio of 2 was found adequate for the better conversion.