This study was performed the real motion and DEM simulation of ball motion using three different types of grinding media with different size and materials in media formation for optimization of process conditions in a traditional ball mill (media ball mill). In the simulation, the rotational speed of the mill, the material of the medium, the velocity of the medium, and the coefficient of friction between the media and the wall of pot were fixed into the actual experimental conditions. The motion of various kinds of grinding media was quantitatively measured by setting the grinding zone defined in the present study on the photographs taken and the snapshot images analyzed in the simulation. In addition, we observed the quantitatively measured value and the changed morphology of the sample and examined the correlation. Therefore, it is suggested to optimize the grinding media which has the greatest influence on the grinding zone under specific experimental conditions.