A semi-pilot hybrid system composed of a photocatalytic reactor and a biofilter was operated under various operating conditions in order to treat malodorous waste air containing both hydrogen sulfide and ammonia which are major air pollutants emitted from composting factories and many publicly owned treatment works (POTW). When both hydrogen sulfide and ammonia contained in malodorous waste air were treated simultaneously by a biofilter system, its performance of ammonia removal was much more poor than that by a biofilter system treating waste air containing only ammonia, unlike its performance of hydrogen sulfide removal. For semi-pilot hybrid system, the removal efficiencies of hydrogen sulfide and ammonia turned out to be ca. 83 and 65%, respectively. Therefore, for semi-pilot hybrid system, the removal efficiencies of hydrogen sulfide and ammonia was increased by ca. 4 and 30%, respectively, compared to those of semi-pilot biofilter system (control). In addition, the maximum elimination capacities of hydrogen sulfide and ammonia for semi-pilot hybrid system turned out to be ca. 60 and 37 g/m3/h, respectively. These maximum elimination capacities of hydrogen sulfide and ammonia were estimated to be ca. 9.1% and ca. 23.3% greater than those for semipilot biofilter system (control), respectively. Therefore, the semi-pilot hybrid system contributed the enhancement of removal efficiency and the maximum elimination capacity of ammonia in a higher degree than that of hydrogen sulfide, compared to the semi-pilot biofilter system.