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Issue
Korean Chemical Engineering Research,
Vol.50, No.5, 759-765, 2012
1,3-프로판디올의 생물학적 생산을 위한 분리공정
Separation Processes of Biologically Produced 1,3-Propanediol
홍연기
바이오 디젤 생산량 증가에 따라 공정 중에 부산물로 발생하는 글리세린의 과잉공급 및 가격 하락이 이루어지고 있다. 이에 따라 글리세린에 기반한 다양한 화학제품생산과 관련된 연구가 활발히 진행되고 있으며 글리세린을 탄소원으로 한 1,3-프로판디올의 생물학적 생산은 그 중 하나이다. 1,3-프로판디올은 지금까지 화학적인 방법을 통해 생산되어 왔으나 생물학적인 방법을 통해 생산될 경우 공정의 친환경성 및 경제성 확보와 더불어 1,3-프로판디올을 중합원료로 하는 PTT (Poly (trimethylene terephthalate))의 바이오폴리머로서의 활용을 가능하게 한다. 그럼에도 글리세린 유래1,3-프로판디올의 생물학적 생산의 경제성에 있어 핵심은 경제적인 분리공정의 수립에 있다. 본 총설에서는 1,3-프로판 디올을 분리하기 위한 공정들에 대한 연구 동향을 소개하고 최근 에너지 절감과 더불어 1,3-프로판디올 분리와 부산물 제거를 동시에 달성할 있는 공정으로 주목받고 있는 수상이성분계 추출에 대한 연구개발 동향 및 전망을 제시하고자 한다.
As the biodiesel production is increasing rapidly, the crude glycerol, which is principal by-product of biodiesel production, has also been generated in a large amount. Many research studies on value-added utilization of glycerol are under investigation. 1,3-Propandiol is a promising chemical which can be produced from fermentation of glycerol because the application of 1,3-propanediol is mainly in the production of bio-PTT (Poly(trimethylene terephthalate). However, the cost of downstream processes in the biological production of 1,3-propanediol can make a high portion in the total production cost. This review summarizes the present state of separation processes in each step studied for the removal of impurities and the recovery of 1,3-propanediol from its fermentation broth. Furthermore, ATPE (Aqueous Two Phases Extraction) process is suggested as an attractive alternative for the primary separation process of 1,3-propanediol because ATPE is convenient for the simultaneous removal of microbial cells and impurities such as salts of organic acids and the separation of 1,3-propanediol from fermentation broth.
Keywords: 1,3-Propanediol; PTT; Glycerol; Downstream Processes; ATPE
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[Cited By]
  1. Hong YK, Korean Chemical Engineering Research, 51(5), 575, 2013
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