| Issue |
Korean Chemical Engineering Research,
Vol.47, No.5, 553-557, 2009
Vol.47, No.5, 553-557, 2009
참당귀(Angelica gigas Nakai) 뿌리 추출물의 화장품소재 특성
Cosmetic Effect of Angelica gigas Nakai Root Extracts
참당귀 뿌리 추출물에서 기능성 화장품소재를 개발하고자 하였다. 기기분석시험을 통하여 참당귀 뿌리 추출물에는 유효성분으로서 decursin과 decursinol angelate가 약 97%로 매우 고농도로 존재하였으며 그 비가 약 3:2로 나타났다. 화장품소재 시험으로는 항산화(DPPH free radical scavenging assay), 미백(Tyrosinase inhibition assay, Melanogenesis inhibition assay), 주름개선(Elastase inhibition assay), 자외선 흡수 및 안전성 시험(MTT assay)이 실시되었다. 참당귀 뿌리 추출물은 15 μg/ml의 농도에서 tyrosine에 대한 tyrosinase 저해효과가 45.2±3.9%, melanin 생성억제 효과가 24.2±12.0%로 미백효과가 우수하였다. 항산화효과는 240 μg/ml의 추출물농도에서 DPPH free radical 소거율이 40.9±9.1%로 비교적 우수하였다. 주름개선 효과는 100 μg/ml의 추출물농도에서 12.7±6.8%로 낮았으며, 자외선 흡수효과도 거의 없었다. 따라서 본 연구를 통하여 참당귀 뿌리 추출물은 화장품용 미백소재로서
가능성을 보여주었다.
Root extracts of Angelica gigas Nakai were tested to see the possibility for functional cosmetic agents. From ethanol extraction method, 97% of decursin and decursinol angelate was obtained, and concentration ratio of decursin to decursinol angelate was about 3:2. To test possibility as a functional cosmetic agent, DPPH free radical scavenging assay, UVA/B absorption, tyrosinase inhibition assay, melanogenesis inhibition assay, elastase inhibition assay and MTT assay were done. Root extracts of Angelica gigas Nakai showed 45.2±3.9% tyrosinase inhibition of tyrosine, and 24.2±12.0% melanin inhibition at 15 μg/ml extract concentration, so that it indicated good whitening effect. DPPH free radical scavenging activity was 40.9±9.1% at 240 μg/ml concentration, which is relatively good. Anti-wrinkle effect was poor such that it was 12.7±6.8% at 100 μg/ml. UVA/B absorption was also negligible. From the research, root extracts of Angelica gigas Nakai showed good potential as a whitening agent.
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[Cited By]
- Kim BY, Kim T, Kang WY, Hyun B, Cheon HY, Kim D, Korean Chemical Engineering Research, 48(3), 327, 2010
- Kim HJ, Kim T, Kang WY, Hyun B, Cheon HY, Kim BY, Kim D, Korean Chemical Engineering Research, 48(4), 413, 2010
- Kim T, Nho HJ, Jun SH, Kim KB, Kim D, Korean Chemical Engineering Research, 48(6), 690, 2010
- Jo EH, Kim IH, Lee JH, Applied Chemistry for Engineering, 28(2), 198, 2017
참고문헌정보(참고문헌, 인용문헌)는 화학공학소재연구정보센터에 의해 제공되고 있습니다.