Supercritical water oxidation of DMMP using continuous flow reactor was studied at temperature ranging from 440 to 540 ℃ and a fixed pressure of 242 bar. The range of residence times in the reactor was from 10 to 26 s, and oxygen excess value varied from -40 to 200％. Destruction efficiencies (DE) of DMMP were greater than 99.7％ at 540 ℃, and increased as the DMMP concentrations were increased. DE of DMMP were significantly affected by oxygen concentration under stoichiometric amount, but showed little difference over stoichiometric amount. On the basis of 30 data with conversions greater than 85％, kinetic correlations for the DE of DMMP were developed. The pre-exponential factor was (1.10±0.76)×106, and the activation energy was 90.66±3.87 kJ/mol, and the reaction orders for DMMP and oxygen were 1.02±0.03, 0.32±0.03, respectively. The model predictions agreed well with the experimental data.