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자외선에 의한 E. coli Double-Lysogen의 용해에 대한 수학적 모델

Mathematical Model for the Cell Lysis of E. Coli Double-lysogen by UV-irradiation

HWAHAK KONGHAK, June 1995, 33(3), 386-392(7)
https://doi.org/NONE
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Abstract

자외선에 의한 E. coli double-lysogen[P90c/(λHL1,434)]의 세포용해율과 자외선 자사량과의 관계를 나타내기 위한 수학적 모델을 제안하였다. Double-lysogen이 조사 받은 자외선량을 정규분포로 나타내었으며, 이로부터 lysogen의 생존율, 용해율, 사멸률을 자외선 조사량에 대한 함수식으로 표현하였다. 이 모델을 이용하여 자외선에 조사된 lysogen의 단백질 생산과 세포용해 특성을 고찰하였으며, 각 매개변수 값을 변화시킴으로서 세포용해에 대한 최적 조건을 예측하였다.
A mathematical model was proposed in order to explain the lytic behaviors of the UV-irradiated E. coli double-lysogen[P90c/(λHL1,434)]. The UV dosage that lysogen had received was represented by the normal distribution, so that the survival, lysis and death fractions of the irradiated lysogen were described by the function of UV dosage. Using this model, the characteristics of the protein production and the cell lysis of the irradiated double-lysogen were studied. Finally, the optimum conditions for the cell lysis were predicted by changing the related parameters.

Keywords

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