AlCl₃ 촉매를 이용한 나프탈렌과 2-methylnaphthalene（2-MN）의 선택적 이소프로필화 반응에서 반응활성과 2,6-체에 대한 선택도는 용액의 극성, 알킬화제의 종류 및 반응시간과 온도에 큰 영향을 받았다. 비극성용매(헥산 또는 이소옥탄)에 반응물(나프탈렌 또는 2-MN)의 2배 정도의 isopropylbromide를 알킬화제로 사용하였을 때 반응활성과 2,6-dialkylnaphthalene의 선택성이 우수하게 나타났다. 또한 반응시간과 반응온도(4℃-60℃ 사이에서)가 증가하면 반응활성과 2,6-DIPN에 대한 선택도가 증가하였다. 반응물로서 2-MN을 사용한 경우가 나프탈렌을 사용한 경우보다 2,6-체에 대한 선택도가 2배 이상 높았다.

The reactivity and selectivity to 2,6-dialkylnaphthalene were affected by the polarity of solvent, alkylating agent, reaction time and reaction temperature in the selective isopropylation of naphthalene or 2-methylnaphthalene（2-MN） with AlCl₃ catalyst. Reaction with isopropylbromide as an alkylating agent in non-polar solvents(hexane or isooctane) was found to be a good system for the higher activity and selectivity to 2,6-dialkylnaphthalene. The reactivity and selectivity were increased as increasing the reaction time and temperature(between 4℃ and 60℃). When 2-MN was used as a substrate, the selectivity to 2,6-DIPN was 2 times higher than naphthalene was used.

Jpn. Patent, 63-211243 to Kawasaki Steet Co.
Jpn. Patent, 63-112527 to Teijin Petrochemical Industries
Jpn. Patent, 60-172937 to Teijin Petrochemical Industries
Jpn. Patent, 50-108246 to Teijin Petrochemical Industries
Kang GB, Yang OB, Song JH, Lee KH, in preparation
Olah GA, Olah JA, J. Am. Chem. Soc., 98, 1839 (1976) 
Godfrey NB, ChemTech, 359 (1972)
Morrison RT, Boyd RN, Organic Chemistry, 4th ed., Allyn and Bacon (1983)