di-isopropyl ether (1)+isooctane (2), ethanol (1)+isooctane (2), di-butyl ether (1)+ethanol (2), di-butyl ether (1)+isooctane (2), propyl vinyl ether (1)+ethanol (2) and propyl vinyl ether (1)+isooctane (2). These data were obtained by using an isothermal flow calorimeter. The experimental binary HE data were well correlated with the Redlich-Kister model, and infinitely dilute partial excess molar enthalpies for each binary were calculated with the fitted Redlich-Kister parameters. Additionally, the isoclines of HE for ternary systems di-isopropyl ether (1)+ethanol (2)+isooctane (3), di-butyl ether (1)+ethanol (2)+isooctane (3) and propyl vinyl ether (1)+ethanol (2)+isooctane (3) at 298.15 K were calculated by using the Radojkovi equation. HE for all the measured systems in this work shows that mixing is endothermic.