.Accidents caused by the domino effect in chemical plants or the petrochemical industry are generally more serious than any other accident. But it is difficult to examine the true factor because the domino effect is influenced by many nonlinear factors. The immediate causes of the domino effect are the peak overpressure, flying objects, and flame. Nonlinearity is inherent in all three causes. However, it is believed that a systematic and mathematical approach can minimize the incidence of the domino effect. We considered the case where there were n-explosive facilities in a given arbitrary rectangular facility site. This paper suggests the positions that can minimize the domino effect using a nonlinear approach. The method initiated an arbitrary number of facilities in addition to the original position, and can search for the position to minimize the domino effect. This paper presents a new computer-aided module, MiniFFECT (MINImization of domino eFFECT).