The main objective of this study was to investigate the optimal design parameters of a multistage porous plate system, numerically and experimentally. Characteristics of pressure drop and collection efficiencyare analyzed with the operation parameters such as the stage number, plate interval, hole diameter and system inlet velocity, etc. In the results, pressure drops of a 5 stage system [2, 2, 3, 2, 2 mm] at v_{s, in}=1.0, 1.2 m/s are shown as 298,428 mmH₂O by the numerical simulation and 259,399 mmH₂O in the experiment. For 5 stage [2, 2, 3, 2, 2 mm] and v_{s, in}=1.0m/s, the overall collection effciencies with the plate interval 4, 10, 15 mm are extimated as 99.5, 96.0, 92.8% computationally and 97.9, 89.2, 85.3%, showing slightly lower efficiency compared to the numerical results due to the particle rescattering effect, experimentally.