This work deals with the investigation of tray efficiency with the gas-liquid-solid three phases and its application in the suspension catalytic distillation (SCD) process. The experimental data of tray efficiency under different conditions were measured by utilizing the desorption of oxygen dissolved in water by air. A method of estimation of tray efficiency for the gas-liquid-solid three phases was put forward and its suitability was also verified. This method was developed of the basis of the AIChE method for gas-liquid two phases. As an application example of this modified AIChE method, the SCD process for synthesizing cumene, based on equilibrium stage (EQ) model incorporating tray efficiency, was simulated.