This study investigated the problem of radiation effects on the flow heat and mass transfer of magnetohydrodynamic steady laminar Marangoni convection in the boundary layer over a disk in the presence of a linear heat source and first-order chemical reactions. The governing partial differential equations of the disk model were established and transformed to a series of ordinary differential equations via suitable self-similar transformations, which were solved numerically by the shooting technique coupled with Runge-Kutta scheme and Newton’s method. The Marangoni number related to temperature and concentration was derived, the effects of the magnetic Hartmann number, Marangoni number, radiation number, heat source number and chemical reaction number related to velocity, temperature, and concentration profiles were analyzed. The results demonstrate that the Hartmann number and Marangoni number have significant impacts on the heat and mass transfer of the Marangoni boundary layer flow. The temperature tends to increase with heat generation and decrease with heat absorption, and it exhibits a delay phenomenon for significant heat generation cases. Negative/positive chemical reactions tended to increase/decrease the concentration, similar to the effect of heat generation/absorption on the temperature.