Pharmaceutical compounds and their derivatives are major pollutants in the environment, as their metabolites affect the terrestrial as well as aquatic organisms in one or another way. In recent times, many papers have discussed the treatment procedures for single pharmaceutical and mixture of pharmaceutical components, but only few papers have discussed the fate and the exposure of pharmaceutical contaminants in our environment. In this paper, we discuss the sources and the forms of pharmaceutical products and their resultant in the environment and their addition to the microbial and to human communities. A detailed discussion of various treatment techniques from conventional to current techniques, their advantages and disadvantages is given here. Researchers are finding the techniques in order to completely degrade the contaminants and their transformed products from the environment. Among the technique, s nanotechnology was found to be an efficient technique, and the combination of nanotechnology with other conventional technologies gives higher removal efficiency.