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Issue
Korean Journal of Chemical Engineering,
Vol.31, No.8, 1289-1305, 2014
Functionalization of magnetic nanoparticles for biomedical applications
Nguyen DT, Kim KS
Interest in utilizing magnetic nanoparticles for biomedical treatments originates from their external controllability of transportation and movement inside biological objects and magnetic heat generation. Advances in nanoparticle and nanotechnology enable us to produce magnetic nanoparticles of specific morphology and to engineer particle surfaces to manipulate their characteristics for specific applications. Intensive investigations and developments have been carried out in improving the quality of magnetic particles, regarding their size, shape, size distribution, their magnetism and their surface. The magnetic nanoparticles with appropriate surface chemistry can conjugate various biomaterials such as drugs, proteins, enzymes, antibodies, or nucleotides to be used for numerous in vivo applications including MRI contrast enhancement, immunoassay, hyperthermia, drug delivery, and cell separation. Here we review both the key technical principles of magnetic nanoparticle synthesis and the ongoing advancement of biomedical treatments using magnetic nanoparticles, specifically, the advancement in controlled drug delivery and hyperthermia.
Keywords: Magnetic Nanoparticles; Controlled Synthesis; Biomedical Applications; Drug Delivery; Hyperthermia
[References]
  1. Yang C, Wu J, Hou Y, Chem. Commun., 47, 5130, 2011
  2. Lu AH, Salabas EL, Schuth F, Angew. Chem. Int. Ed., 46, 1222, 2007
  3. Laurent S, Forge D, Port M, Roch A, Robic C, Elst LV, Muller RN, Chem. Rev., 108(6), 2064, 2008
  4. Lee N, Hyeon T, Chem. Soc. Rev., 41, 2575, 2012
  5. Sun C, Lee JSH, Zhang M, Adv. Drug Deliv. Rev., 60, 1252, 2008
  6. Kumar CSSR, Mohammad F, Adv. Drug Deliv. Rev., 63, 789, 2011
  7. Massart R, IEEE Trans. Magn., 17, 1247, 1981
  8. Vayssieres L, Chaneac C, Tronc E, Jolivet JP, J. Colloid Interface Sci., 205(2), 205, 1998
  9. Gnanaprakash G, Mahadevan S, Jayakumar T, Kalyanasundaram P, Philip J, Raj B, Mater. Chem. Phys., 103(1), 168, 2007
  10. Jolivet JP, Belleville P, Tronc E, Livage J, Clays Clay Miner., 40, 531, 1992
  11. Jolivet JP, Chaneac C, Tronc E, Chem. Commun., 5, 481, 2004
  12. Sun SH, Zeng H, J. Am. Chem. Soc., 124(28), 8204, 2002
  13. Sun SH, Zeng H, Robinson DB, Raoux S, Rice PM, Wang SX, Li GX, J. Am. Chem. Soc., 126(1), 273, 2004
  14. Xu ZC, Shen CM, Hou YL, Gao HJ, Sun SS, Chem. Mater., 21, 1778, 2009
  15. Jana NR, Chen YF, Peng XG, Chem. Mater., 16, 3931, 2004
  16. Cai W, Wan JQ, J. Colloid Interface Sci., 305(2), 366, 2007
  17. Hyeon T, Lee SS, Park J, Chung Y, Bin Na H, J. Am. Chem. Soc., 123(51), 12798, 2001
  18. Park J, Lee E, Hwang NM, Kang M, Kim SC, Hwang Y, Park JG, Noh HJ, Kim JY, Park JH, Hyeon T, Angew. Chem. Int. Ed., 44, 2872, 2005
  19. Park J, An KJ, Hwang YS, Park JG, Noh HJ, Kim JY, Park JH, Hwang NM, Hyeon T, Nat. Mater., 3(12), 891, 2004
  20. Kwon SG, Piao Y, Park J, Angappane S, Jo Y, Hwang NM, Park JG, Hyeon T, J. Am. Chem. Soc., 129(41), 12571, 2007
  21. Ge J, Hu Y, Biasini M, Beyermann WP, Yin Y, Angew. Chem. Int. Ed., 46, 4342, 2007
  22. Zhang L, He R, Gu HC, Mater. Res. Bull., 41(2), 260, 2006
  23. Swaminathan R, Willard MA, Mchenry ME, Acta Mater., 54, 807, 2006
  24. Qi HP, Chen QW, Wang MS, Wen MH, Xiong J, J. Phys. Chem. C, 113, 17301, 2009
  25. Kim D, Lee N, Park M, Kim BH, An K, Hyeon T, J. Am. Chem. Soc., 131(2), 454, 2009
  26. Zhao L, Zhang H, Xing Y, Song S, Yu S, Shi W, Guo X, Yang J, Lei Y, Cao F, Chem. Mater., 20, 198, 2008
  27. Li X, Si Z, Lei Y, Tang J, Wang S, Su S, Song S, Zhao L, Zhang H, Cryst. Eng. Comm., 12, 2060, 2010
  28. Qu XF, Yao QZ, Zhou GT, Fu SQ, Huang JL, J. Phys. Chem. C, 114, 8734, 2010
  29. Palchoudhury S, Xu Y, Goodwin J, Bao Y, J. Appl. Phys., 109, 07E314, 2011
  30. Caruso F, Spasova M, Susha A, Giersig M, Caruso RA, Chem. Mater., 13, 109, 2001
  31. Huang ZB, Tang FQ, J. Colloid Interface Sci., 281(2), 432, 2005
  32. Peng S, Sun S, Angew. Chem. Int. Ed., 46, 4155, 2007
  33. Huang J, Chen W, Zhao W, Li Y, Li X, Chen C, J. Phys. Chem. C, 113(35), 12067, 2009
  34. Fan HJ, Gcsele U, Zacharias M, Small, 3, 1660, 2007
  35. Wang CM, Baer DR, Thomas LE, Amonette JE, Antony J, Qiang Y, Duscher G, J. Appl. Phys., 98, 094308, 2005
  36. Nakamura R, Tokozakura D, Nakajima H, Lee JG, Mori H, J. Appl. Phys., 101, 074303, 2007
  37. Nakamura R, Lee JG, Tokozakura D, Mori H, Nakajima H, Mater. Lett., 61, 1060, 2007
  38. Piao Y, Kim J, Bin Na H, Kim D, Baek JS, Ko MK, Lee JH, Shokouhimehr M, Hyeon T, Nat. Mater., 7(3), 242, 2008
  39. Wu HX, Zhang SJ, Zhang JM, Liu G, Shi JL, Zhang LX, Cui XZ, Ruan ML, He QJ, Bu WB, Adv. Funct. Mater., 21(10), 1850, 2011
  40. Zhu LP, Xiao HM, Zhang WD, Yang G, Fu SY, Cryst. Growth Des., 8, 957, 2008
  41. Liu S, Xing R, Lu F, Rana RK, Zhu JJ, J. Phys. Chem. C, 113, 21042, 2009
  42. Hu P, Yu L, Zuo A, Guo C, Yuan F, J. Phys. Chem. C, 113, 900, 2009
  43. Cheng C, Xu F, Gu H, New J. Chem., 35, 1072, 2011
  44. Chen XY, Zhang ZJ, Li XX, Shi CW, Chem. Phys. Lett., 422(1-3), 294, 2006
  45. Lin X, Ji G, Liu Y, Huang Q, Yang Z, Du Y, Cryst. Eng. Comm., 14, 8658, 2012
  46. Nguyen DT, Kim KS, AIChE J., 59(10), 3594, 2013
  47. Nguyen DT, Kim KS, J. Nanosci. Nanotechnol., 13, 5773, 2013
  48. Nguyen DT, Park DW, Kim T, Kim KS, J. Nanosci. Nanotechnol., In Press.
  49. Coey JMD, Magnetism and magnetic materials, Cambridge University Press, 2009
  50. Leslie-Pelecky DL, Chem. Mater., 8, 1770, 1996
  51. Bean CP, Livingston JD, J. Appl. Phys., 30, 120, 1959
  52. Krishnan KM, IEEE Trans. Magn., 46, 2523, 2010
  53. Rosensweig RE, J. Magn. Magn. Mater., 252, 370, 2002
  54. Yoo D, Lee JH, Shin TH, Cheon J, Acc. Chem. Res., 44, 863, 2011
  55. Margulies DT, Parker FT, Spada FE, Goldman RS, Li J, Sinclair R, Berkowitz AE, Phys. Rev. B, 53, 9175, 1996
  56. Kodama RH, J. Magn. Magn. Mater., 200, 359, 1999
  57. Yuan Y, Rende D, Altan CL, Bucak S, Ozisik R, Borca-Tasciuc DA, Langmuir, 28(36), 13051, 2012
  58. LaConte LEW, Nitin N, Zurkiya O, Caruntu D, O’Connor CJ, Hu XP, Bao G, J. Magn. Reson. Imaging, 26, 1634, 2007
  59. Duan H, Kuang M, Wang X, Wang YA, Mao H, Nie S, J. Phys. Chem. C, 112, 8127, 2008
  60. Hochepied JF, Pileni MP, J. Appl. Phys., 87, 2472, 2000
  61. Hochepied JF, Bonville P, Pileni MP, J. Phys. Chem. B, 104(5), 905, 2000
  62. Beji Z, Hanini A, Smiri LS, Gavard J, Kacem K, Villain F, Greneche JM, Chau F, Ammar S, Chem. Mater., 22, 5420, 2010
  63. Jang JT, Nah H, Lee JH, Moon SH, Kim MG, Cheon J, Angew. Chem. Int. Ed., 48, 1234, 2009
  64. Nogus J, Sort J, Langlais V, Skumryev V, Surinach S, Munoz JS, Baro MD, Phys. Rep., 422, 65, 2005
  65. Yoon TJ, Lee H, Shao H, Weissleder R, Angew. Chem. Int. Ed., 50, 4663, 2011
  66. Lacroix LM, Huls NF, Ho D, Sun X, Cheng K, Sun S, Nano Lett., 11, 1641, 2011
  67. Gupta AK, Gupta M, Biomaterials, 26, 3995, 2005
  68. Oh JK, Park JM, Prog. Polym. Sci., 36, 168, 2011
  69. Mahmoudia M, Sant S, Wang B, Laurent S, Sen T, Adv. Drug Deliv. Rev., 63, 24, 2011
  70. Li Z, Wei L, Gao MY, Lei H, Adv. Mater., 17(8), 1001, 2005
  71. Mohapatra S, Pramanik N, Ghosh SK, Pramanik P, J. Nanosci. Nanotechnol., 6, 823, 2006
  72. Ziolo RF, Giannelis EP, Weinstein BA, O’Horo MP, Ganguly BN, Mehrotra V, Russell MW, Huffman DR, Science, 257, 219, 1992
  73. Llanes F, Ryan DH, Marchessault RH, Int. J. Biol. Macromol., 27, 35, 2000
  74. Nishio Y, Yamada A, Ezaki K, Miyashita Y, Furukawa H, Horie K, Polymer, 45(21), 7129, 2004
  75. Finotelli PV, Morales MA, Rocha-Leao MH, Saitovitch EMB, Rossi AM, Mater. Sci. Eng., 24, 625, 2004
  76. Philipse AP, Vanbruggen MP, Pathmamanoharan C, Langmuir, 10(1), 92, 1994
  77. Santra S, Tapec R, Theodoropoulou N, Dobson J, Hebard A, Tan WH, Langmuir, 17(10), 2900, 2001
  78. Kohler N, Fryxell GE, Zhang MQ, J. Am. Chem. Soc., 126(23), 7206, 2004
  79. Lee H, Lee E, Kim DK, Jang NK, Jeong YY, Jon S, J. Am. Chem. Soc., 128(22), 7383, 2006
  80. Lee H, Yu MK, Park S, Moon S, Min JJ, Jeong YY, Kang HW, Jon S, J. Am. Chem. Soc., 129(42), 12739, 2007
  81. Li GL, Zeng DLM, Wang L, Zong BY, Neoh KG, Kang ET, Macromolecules, 42(21), 8561, 2009
  82. Zhou J, Meng L, Lu Q, Fu J, Huang X, Chem. Commun., 6370, 2009
  83. Xu ZC, Hou YL, Sun SH, J. Am. Chem. Soc., 129(28), 8698, 2007
  84. Goon IY, Lai LMH, Lim M, Munroe P, Gooding JJ, Amal R, Chem. Mater., 21, 673, 2009
  85. Nguyen DT, Park DW, Kim KS, J. Nanosci. Nanotechnol., 11, 7214, 2011
  86. Nguyen DT, Kim DJ, Kim KS, Micron, 42, 207, 2011
  87. Moghimi SM, Biochem. Biophys. Acta, 1336, 1, 1997
  88. Li JT, Caldwell KD, Rapoport N, Langmuir, 10(12), 4475, 1994
  89. Moghimi SM, Hunter AC, Trends Biotechnol., 18, 412, 2000
  90. Veiseh O, Sun C, Gunn J, Kohler N, Gabikian P, Lee D, Bhattarai N, Ellenbogen R, Sze R, Hallahan A, Olson J, Zhang MQ, Nano Lett., 5, 1003, 2005
  91. Sun C, Sze R, Zhang MQ, J. Biomed. Mater. Res. A, 78, 550, 2006
  92. Lutz JF, Stiller S, Hoth A, Kaufner L, Pison U, Cartier R, Biomacromolecules, 7(11), 3132, 2006
  93. Shen T, Weissleder R, Papisov M, Bogdanov A, Brady TJ, Magn. Reson. Med., 29, 599, 1993
  94. Josephson L, Tung CH, Moore A, Weissleder R, Bioconjugate Chem., 10, 186, 1999
  95. Wunderbaldinger P, Josephson L, Weissleder R, Bioconjugate Chem., 13, 264, 2002
  96. Schellenberger EA, Bogdanov A, Hogemann D, Tait J, Weissleder R, Josephson L, Mol. Imaging, 1, 102, 2002
  97. Kim EH, Lee HS, Kwak BK, Kim BK, J. Magn. Magn. Mater., 289, 328, 2005
  98. Kim EH, Ahn Y, Lee HS, J. Alloys Compd., 434, 633, 2007
  99. Bhattarai SR, Kim SY, Jang KY, Lee KC, Yi HK, Lee DY, Kim HY, Hwang PH, J. Virol. Methods, 147, 213, 2008
  100. Sun C, Lee JSH, Zhang M, Adv. Drug Deliv. Rev., 60, 1252, 2008
  101. Yu MK, Jeong YY, Park J, Park S, Kim JW, Min JJ, Kim K, Jon S, Angew. Chem. Int. Ed., 47, 5362, 2008
  102. Kohler N, Sun C, Wang J, Zhang MQ, Langmuir, 21(19), 8858, 2005
  103. Lu CW, Hung Y, Hsiao JK, Yao M, Chung TH, Lin YS, Wu SH, Hsu SC, Liu HM, Mou CY, Yang CS, Huang DM, Chen YC, Nano Lett., 7, 149, 2007
  104. Lee JH, Jun YW, Yeon SI, Shin JS, Cheon J, Angew. Chem. Int. Ed., 45, 8160, 2006
  105. Josephson L, Kircher MF, Mahmood U, Tang Y, Weissleder R, Bioconjugate Chem., 13, 554, 2002
  106. Josephson L, Tung CH, Moore A, Weissleder R, Bioconjugate Chem., 10, 186, 1999
  107. Hogemann D, Josephson L, Weissleder R, Basilion JP, Bioconjugate Chem., 11, 941, 2000
  108. Kang HW, Josephson L, Petrovsky A, Weissleder R, Bogdanov AJ, Bioconjugate Chem., 13, 122, 2002
  109. Schellenberger EA, Sosnovik DE, Weissleder R, Josephson L, Bioconjugate Chem., 15, 1062, 2004
  110. Jain RK, Annu. Rev. Biomed. Eng., 1, 241, 1999
  111. Jain RK, J. Controlled Release, 74, 7, 2001
  112. Thorek DLJ, Chen A, Czupryna J, Tsourkas A, Ann. Biomed. Eng., 34, 23, 2006
  113. McCarthy JR, Weissleder R, Adv. Drug Deliv. Rev., 60, 1241, 2008
  114. Berry CC, J. Phys. D: Appl. Phys., 42, 224003, 2009
  115. Corchero J, Villaverde A, Trends Biotechnol., 27, 468, 2009
  116. Toti US, Guru BR, Grill AE, Panyam J, Mol. Pharm., 7, 1108, 2010
  117. Yang X, Grailer JJ, Rowland IJ, Javadi A, Hurley SA, Steeber DA, Gong S, Biomaterials, 31, 9065, 2010
  118. Cheng D, Hong G, Wang W, Yuan R, Ai H, Shen J, Liang B, Gao J, Shuai X, J. Mater. Chem., 21, 4796, 2011
  119. Chertok B, David AE, Huang Y, Yang VC, J. Control. Release, 122, 315, 2007
  120. Chertok B, David AE, Yang VC, J. Controlled Release, 155, 393, 2011
  121. Todd T, Zhen Z, Tang W, Chen H, Wang G, Chuang YJ, Deaton K, Pan Z, Xie J, Nanoscale, 6, 2073, 2014
  122. Medeiros SF, Santos AM, Fessi H, Elaissari A, Int. J. Pharm., 403, 139, 2011
  123. Nguyen DT, Charinpanitkul T, Park DW, Kim KS, J. Nanosci. Nanotechnol., In Press.
  124. Liu S, Xing R, Lu F, Rana RK, Zhu JJ, J. Phys. Chem. C, 113, 21042, 2009
  125. Zhang X, Clime L, Roberge H, Normandin F, Yahia LH, Sacher E, Veres T, J. Phys. Chem. C, 115, 1436, 2011
  126. Cheng K, Peng S, Xu CJ, Sun SH, J. Am. Chem. Soc., 131(30), 10637, 2009
  127. Liu TY, Hu SH, Liu TY, Liu DM, Chen SY, Langmuir, 22, 5974, 2006
  128. Hu SH, Liu TY, Liu DM, Chen SY, J. Controlled Release, 121, 181, 2007
  129. De Paoli VM, Lacerda SHD, Spinu L, Ingber B, Rosenzweig Z, Rosenzweig N, Langmuir, 22(13), 5894, 2006
  130. Regmi R, Bhattarai SR, Sudakar C, Wani AS, Cunningham R, Vaishnava PP, Naik R, Oupicky D, Lawes G, J. Mater. Chem., 20, 6158, 2010
  131. Liu TY, Hu SH, Liu DM, Chen SY, Chen IW, Nano Today, 4(1), 52, 2009
  132. Liu TY, Liu KH, Liu DM, Chen SY, Chen IW, Adv. Funct. Mater., 19(4), 616, 2009
  133. Hoare T, Santamaria J, Goya GF, Irusta S, Lin D, Lau S, Padera R, Langer R, Kohane DS, Nano Lett., 9, 3651, 2009
  134. Thomas CR, Ferris DP, Lee JH, Choi E, Cho MH, Kim ES, Stoddart JF, Shin JS, Cheon J, Zink JI, J. Am. Chem. Soc., 132(31), 10623, 2010
  135. Huang H, Delikanli S, Zeng H, Ferkey DM, Pralle A, Nat. Nanotechnol., 5(8), 602, 2010
  136. Gilchrist RK, Medal R, Shorey WD, Hanselman RC, Parott JC, Taylor CB, Ann. Surg., 146, 596, 1957
  137. Overgaard K, Overgaard J, Eur. J. Cancer, 8, 65, 1972
  138. Chan DCF, Kirpotin DB, Bunn PA, J. Magn. Magn. Mater., 122, 374, 1993
  139. Jordan A, Wust P, Fahling H, John W, Hinz A, Felix R, Int. J. Hyperthermia, 9, 51, 1993
  140. Suzuki M, Shinkai M, Honda H, Kobayashi T, Melanoma Res., 13, 129, 2003
  141. Ito A, Shinkai M, Honda H, Yoshikawa K, Saga S, Wakabayashi T, Yoshida J, Kobayashi T, Cancer Immunol. Immun., 52, 80, 2003
  142. Sivasai B, Rajashekar R, Hongwang W, Thilani SN, Raj-Kumar D, Marla P, Franklin KO, Brandon W, Xiaoxuan L, Olga KB, Masaaki T, Viktor C, Stefan BH, Deryl TL, BMC Cancer, 10, 1, 2010
  143. Ivkov R, DeNardo SJ, Daum W, Foreman AR, Goldstein RC, Nemkov VS, DeNardo GL, Clin. Cancer Res., 11, 7093s, 2005
  144. DeNardo SJ, DeNardo GL, Natarajan A, Miers LA, Foreman AR, Gruettner C, Adamson GN, Ivkov R, J. Nucl. Med., 48, 437, 2007
  145. Brezovich IA, Med. Phys. Monogr., 1682, 1988
  146. Hergt R, Dutz SJ, J. Magn. Magn. Mater., 311, 187, 2007
  147. Kita E, Oda T, Kayano T, Sato S, Minagawa M, Yanagihara H, Kishimoto M, Mitsumata C, Hashimoto S, Yamada K, Ohkohchi N, J. Phys. D: Appl. Phys., 43, 474011, 2010
  148. Vallejo-Fernandez G, Roca AG, Hussain S, Timmis J, Patel V, O’Grady K, J. Phys. D: Appl. Phys., 46, 312001, 2013
  149. Riviere C, Wilhelm C, Cousin F, Dupuis V, Gazeau F, Perzynski R, Eur. Phys. J. E, 22, 1, 2007
  150. Wilhelm C, Fortin JP, Gazeau F, J. Nanosci. Nanotechnol., 7, 2933, 2007
  151. Fortin JP, Gazeau F, Wilhelm C, Eur. Biophys. J., 37, 223, 2008
  152. Hiergeist R, Andra W, Buske N, Hergt R, Hilger I, Richter U, Kaiser W, J. Magn. Magn. Mater., 201, 420, 1999
  153. Mornet S, Vasseur S, Grasset F, Duguet E, Mater. Chem., 14, 2161, 2004
  154. Laurent S, Dutz S, Hafeli UO, Mahmoudi M, Adv. Colloid Interface Sci., 166, 8, 2011
  155. Deatsch AE, Evans BA, J. Magn. Magn. Mater., 354, 163, 2014
  156. Habib AH, Ondeck CL, Chaudhary P, Bockstaller MR, McHenry ME, J. Appl. Phys., 103, 07A307, 2008
  157. Ma M, Wu Y, Zhou J, Sun Y, Zhang Y, Gu N, J. Magn. Magn. Mater., 268, 33, 2004
  158. Gonzales-Weimuller M, Zeisberger M, Krishnan KM, J. Magn. Magn. Mater., 321, 1947, 2009
  159. Gonzalez-Fernandez MA, Torres TE, Andres-Verges M, Costo R, de la Presa P, Serna CJ, Moralesa MP, Marquina C, Ibarra MR, Goya GF, J. Solid State Chem., 182, 2779, 2009
  160. Bae KH, Park M, Do MJ, Lee N, Ryu JH, Kim GW, Kim CG, Park TG, Hyeon T, ACS Nano, 6, 5266, 2012
  161. Kuznetsov AA, Shlyakhtin OA, Brusentsov NA, Kuznetsov OA, Eur. Cell. Mater., 3(Suppl. 2), 75, 2002
  162. Hejase H, Hayek SS, Qadri S, Haik Y, J. Magn. Magn. Mater., 324, 3620, 2012
  163. Apostolov AT, Apostolova IN, Wesselinova JM, Eur. Phys. J. B, 86, 483, 2013
  164. Akin Y, Obaidat IM, Issa B, Haik Y, Cryst. Res. Technol., 44, 386, 2009
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  4. Bohara RA, Thorat ND, Pawar SH, Korean Journal of Chemical Engineering, 33(1), 216, 2016
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