Issue
Korean Journal of Chemical Engineering,
Vol.31, No.3, 402-411, 2014
Pressure distribution and wall shear stress in stenosis and abdominal aortic aneurysm by computational fluid dynamics modeling (CFD)
The models of stenosed blood vessel with three different types of stenosis types have been modeled to investigate blood flow characteristics. The study was performed to investigate various hemodynamics, such as pressure and wall shear stress (WSS), with the change of stenosis ratio and Reynolds numbers (Re). The results of modeling, the minimum WSS occurred in different regions according to the stenosis types. The change of the diameter of blood vessel showed up in the pre-stenotic region by elastic behavior characteristics of blood vessels. Also, when the thickness of wall of blood vessel is 2 mm, the radius of blood vessel is increased by approximately two-times. As atherosclerosis progresses, the wall of blood vessels gradually loses elasticity and then the thickness of blood vessels gets thinner.
[References]
  1. Giddens DP, Zarins CK, Glagov S, J. Biomech. Eng. T. ASME, 115, 588, 1993
  2. Lee BK, Kwon HM, Kim DS, Yoon YW, Seo JK, Kim IJ, Roh HW, Suh SH, Yoo SS, Kim HS, Yonsei Med. J., 39(2), 166, 1998
  3. Zendehbudi GR, Moayeri MS, J. Biomech., 32, 959, 1999
  4. Lee BK, Kwon HM, Hong BK, Park BE, Sug SH, Cho MT, Lee CS, Kim MC, Kim CJ, Yoo SS, Kim HS, Yonsei Med. J., 42(4), 375, 2001
  5. Kim HK, Park JC, Kim SS, Choi HS, Sim DS, Yoon NS, Yoon HJ, Hong YJ, Park HY, Kim JH, Yan YG, Korean J. Int. Med., 77, 68, 2009
  6. Ku DN, Giddens DP, Zarins CK, Glagov S, Arteriosclerosis, 5, 293, 1985
  7. Bluestein D, Alemu Y, Avrahami I, Gharib M, Dumont K, Ricotta JJ, Einav S, J. Biomech., 41, 1111, 2008
  8. Fry DL, A Ciba Foundation Symp., ASP, Amsterdam, The Netherlands, 40, 1972
  9. Caro CG, Fitz-Gerald FM, Schroter RC, Proc. R. Soc. B., 177, 109, 1971
  10. Thompson RW, Geraghty PJ, Lee JK, Curr. Prob. Surg., 39(2), 110, 2002
  11. Fillinger MF, Marra SP, Raghavan ML, Kennedy FE, J. Vasc. Surg., 37(4), 724, 2003
  12. Oh SE, Lee KR, J. Biomed. Eng. Res., 21(2), 181, 2000
  13. Valencia A, Villanueva M, Int. Commun. Heat Mass Transf., 33, 966, 2006
  14. Kim SJ, Park YR, Kim SJ, Kang HS, Kim JS, Oh SH, Kang SJ, Kim GB, JKAIS, 13(5), 2285, 2012
  15. Park YR, Kim SJ, Kim SJ, Kim JS, Kang HS, Kim GB, J. Biomed. Nanotechnol., 9, 1137, 2013
  16. Choi JH, Lee CS, Kim CJ, J. Biomed. Eng. Res., 21, 363, 1997
  17. Seo SH, Park JK, Roh HW, Lee BK, Kwon HM, Trans. KSME, B, 34(10), 893, 2010
  18. David NK, Ann. Rev. Fluid Mech., 29, 399, 1997
  19. Kirpalani A, Park H, Butany J, Johnston KW, J. Biomech. Eng., 121(4), 370, 1999
  20. Manimaran R, WASET, 49, 957, 2011
  21. Sud VK, Sekhon GS, Bull. Math. Biol., 47, 35, 1985
  22. Ro KC, Ryou HS, Korea-Aust. Rheol. J., 21(3), 175, 2009
  23. Li ZY, Gillard JH, J. Am. Coll. Cardiol., 52(6), 498, 2008
  24. Li ZY, Taviani V, Tang T, Sadat U, Young V, Patterson A, Graves M, Gillrd JH, BJR, 82, 39, 2009
  25. Wootton DM, Ku DN, Annu. Rev. Biomed. Eng., 1, 299, 1999
  26. Ojha M, J. Biomech., 26, 1379, 1993
  27. Mittal M, Simmons SP, Udaykumar HS, J. Biomech. Eng. T. ASME, 123, 325, 2001
  28. Cheng GC, Loree HM, Kamm RD, Fishbein MC, Lee RT, Circulation, 87, 1179, 1993
  29. Lee RT, Loree HM, Cheng GC, Lieberman EH, Jaramillo N, Schoen FJ, J. Am. Coll. Cardiol., 21, 777, 1993
  30. Li ZY, Howarth S, Trivedi RA, UK-I JM, Graves MJ, Brown A, Wang L, Gillard JH, J. Biomech., 39, 2611, 2006
  31. Li ZY, Howarth SP, Tang T, Gillard JH, Stroke, 37, 1195, 2006
  32. Li ZY, Howarth SP, Tang T, Graves MJ, UK-I JM, Trivedi RA, Kirkpatrick PJ, Gillard JH, J. Vasc. Surg., 45, 768, 2007
  33. MRC European Carotid Surgery, Lancet, 337, 1235, 1991
  34. North Americas Symptomatic Carotid Endarterectomy Trial collaborators, N. Eng. J. Med., 325, 445, 445, 1991