2-Methyl-4-methoxy aniline, an intermediate of the ODB-2 was synthesized from various aromatic compounds by using acid and base catalysts. With liquid sulfuric acid catalyst and Pt/C hydrogenation catalyst, an 80% yield was obtained from ortho-nitro toluene. The reaction followed the Bemberger reaction mechanism and the byproduct produced was toluidine resulted from a complete reduction of the reactant. To obtain 2-methyl-4-methoxy aniline from 3-methyl-4-nitro phenol, a one step reaction using NaOH and Pt/C hydrogenation catalysts was carried out under hydrogen pressure. The rate determining step was the alylation of the hydroxyl group in the phenol compound to form the corresponding anisole and the yield was 80%. In this route, however, the only byproduct formed, 3-methyl-4-amino phenol could be easily separated from the reaction mixture by washing with water and converted to the final desired product by a simple methoxylation with DMSA to give to an overall yield of 92%.