The concentration distribution in a catalytic packed bed with packing was studied. The resistance to flow in the bed, packed with activated alumina particles to catalyze ethanol degydration reaction, varied by inserting sereen-packing and different size particle section. It was found that the velocity-and concentra-tion-profiles were non-uniform due to the variation of void fraction near the wall. The effect of inserting the screen-packing in the bed enabled velocity-and concentration-profiles to be uniformly distributed over the bed. the governing equations for momentum-and mass-transport in the fixed be and the fixed bed containing a screen-packing were numercasslly solved to demonstrate the effects of the void fraction and the screen-packing inseted in the bed. Effluent ethanol concentrations, measured by ethanol detector tube, were found to be varied with radial position in a manner consistent with the modeling equations.