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Search / Korean Journal of Chemical Engineering
HWAHAK KONGHAK,
Vol.39, No.4, 390-396, 2001
천연물에 포함된 유용성분의 용해도 예측
Estimation of Solubility of the Useful Components in Some Natural Products
강지훈, 정성택, 노경호
건강에 관심을 갖는 인구의 증가와 기호의 다양화에 의해 천연물의 수요가 점차 확대되어 가고 있다. 천연물에 포함된 주요한 유용성분들은 acanthoside-D, β-carotene, (+)catechin, daidzein, (-)epicatechin gallate, (-)epigallocatechin, (-)epigallocatechin gallate, genistein, indole-3-carbinol, d-limonene, perillyl alcohol, taxol, vitamin E 등이 있다. 화학적인 구조에 의한 유용성분의 용해도 매개변수를 예측하는 방법을 몇가지 계산과 함께 나타내었다. 이러한 기술은 유용성분과 용매사이의 용해도를 예측할 수 있는 적절한 방법으로 기대된다. 용해도 매개변수의 연구는 천연물로부터 유용성분을 추출하고 분리하기 위한 고순도 분리 공정에 이용될 것이다.
The demand on the natural product has increased due to the concern on the health and to meet various personal preferences. Among the natural products, the most useful components are acanthoside-D, β-carotene, (+)catechin, daidzein, (-)epicatechin gallate, (-)epigallocatechin, (-)epigallocatechin gallate, genistein, indole-3-carbinol, d-limonene, perillyl alcohol, taxol, vitamin E. A group-contribution technique for the calculation of solubility parameter for useful components is presented along with some calculations. The proposed method was found to be good in estimating solubilities of useful components in solvents. The study on the solubility parameter may be utilized for high-purity separation processes in order to separate and extract useful components from natural products.
Keywords: Solubility Prediction; Solubility Parameter; Natural Products
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[Cited By]
  1. Kang JH, Chung ST, Row KH, Journal of Industrial and Engineering Chemistry, 8(4), 354, 2002
  2. Jung YW, Lee HY, Lee MJ, Song AR, Bae JH, Clean Technology, 12(4), 250, 2006
  3. Jung YW, Lee HY, Bae JH, Clean Technology, 13(2), 143, 2007
  4. Kim DJ, Oh HS, Kim JK, Park MJ, Lee M, Koo KK, Clean Technology, 13(4), 257, 2007
  5. Min HJ, Shin JH, Bae JH, Kim HG, Lee HJ, Clean Technology, 14(3), 184, 2008
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