Mathematical modeling and computer simulation were carried out on the coupled reaction system comprised of chromatophore and NAD kinase. An empirical kinetic model was used for the chromatophore whereas analytically derived models were employed for other catalytic components of the system. Myokinase was also included as a system component because of the difficulty in its complete separation from the chromatophore and NAD kinase.
The effect of the relative ratio of the catalytic activities of the system on the overall production of NADP was studied. The time course behaviour of the biochemical species of the system was also obtained from the simulation results.
Experimental data and the results of the computer simulation were compared.