To develop a high-performance structured catalyst, the fine grinding characteristics of alumina was investigated by a stirred-ball attrition mill. The grinding kinetics approach was successfully applied to the analysis of particle size distributions obtained under various grinding times. Particle size of alumina decreased with increasing grinding time and BET surface area increased with increasing the time. It was found that grinding rate constant decreased with increasing the solid content and media size. The particle size distributions estimated from grinding rate constant were in good agreement with the experimental data. It was found that the pH-value of the product suspension slightly increased due to increasing the specific surface area during the comminution. It was identified that nano-size alumina was produced by means of the stirred-ball attrition mill.