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- In relation to this article, we declare that there is no conflict of interest.
- Publication history
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Received September 14, 2023
Accepted October 18, 2023
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This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/bync/3.0) which permits
unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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Synthesis and Characterization of Silver Nanoparticles from Marine S treptomyces parvisporogenes KL3 for Eff ective Antibacterial and Larvicidal Applications
Abstract
Recent studies have emphasized the application of nanoscience and nanotechnology to disease prevention, diagnosis, and
treatment. This study examined the use of marine actinobacteria in the synthesis of silver nanoparticles (AgNPs). UV–Vis
spectrophotometry, Fourier infrared spectroscopy, X-ray diff raction, scanning electron microscopy, and energy dispersive
X-ray spectroscopy were used to characterize the primary structure, crystalline nature, functional groups, shape, and elemental
signal of the synthesized AgNPs. The mean particle diameter of the AgNPs was measured, and the size was found to be
between 23 and 27 nm. The antibacterial activity of the AgNPs was evaluated; it showed enhanced inhibitory activity against
Escherichia coli , Bacillus subtilis , and Klebsiella pneumoniae . At an AgNP concentration of 40 g/mL, the test pathogen
growth was completely inhibited. The larvicidal property of the synthesized AgNPs showed enhanced activity against An.
stephensi (LC5017.511 and LC9050.572), A. aegypti (LC50 22.481 and LC90 61.920), and Cx. quinquefasciatus (LC50
29.548 and LC90 73.123). By analyzing the phenotypic data, the 16S rRNA gene sequence, and the phylogenetic data, the
probable isolate was also determined to be Streptomyces parvisporogenes KL3. The study results prove that biosynthesized
AgNPs can be used as eff ective antibacterial and larvicidal agents in drug formulation.
